Fig. 2

Symptoms profiles. A Heat map (left) representing proportional occurrence of specific symptoms across the first anaphylactic response of uniphasic, non-anaphylactic biphasic reaction responders. Biphasic patients were more likely (p = 0.0361, 2-way ANOVA with Tukey’s Multiple Comparisons test) to report “other mouth/throat swelling” than non-anaphylactic biphasics. Heat map (right) representing proportional occurrence of specific symptoms across the second anaphylactic response of non-anaphylactic biphasic and biphasic responders. The secondary anaphylactic reaction of biphasics had significantly less symptoms (p < 0.0001, 2-way ANOVA with Tukey’s Multiple Comparison’s test) than non-anaphylactic biphasics. C Graph displaying the proportion of symptoms experienced by biphasic responders comparing their first and second anaphylaxis reactions. There were six symptoms which were significantly decreased in biphasic responders’ second (red) reaction vs first (blue)