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  1. In Canada, severe asthma affects an estimated 5–10% of people with asthma and is associated with frequent exacerbations, poor symptom control and significant morbidity from the disease itself, as well as the h...

    Authors: K. Godbout, M. Bhutani, L. Connors, C. K. N. Chan, C. Connors, D. Dorscheid, G. Dyck, V. Foran, A. G. Kaplan, J. Reynolds and S. Waserman
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:12
    Content type: Research Published on:

  3. Chronic obstructive pulmonary disease (COPD) affects up to 10% of Canadians. Patients with COPD may present with secondary humoral immunodeficiency as a result of chronic disease, poor nutrition or frequent co...

    Authors: Nami Shrestha Palikhe, Malcena Niven, Desi Fuhr, Tristan Sinnatamby, Brian H. Rowe, Mohit Bhutani, Michael K. Stickland and Harissios Vliagoftis
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:10
    Content type: Research Published on:

  4. High-fidelity simulations based on real-life clinical scenarios have frequently been used to improve patient care, knowledge and teamwork in the acute care setting. Still, they are seldom included in the aller...

    Authors: Ana M. Copaescu, Francois Graham, Nathalie Nadon, Rémi Gagnon, Arnaud Robitaille, Mohamed Badawy, David Claveau, Anne Des Roches, Jean Paradis, Matthieu Vincent and Philippe Bégin
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:9
    Content type: Research Published on:

  5. House dust mite (HDM) induces greater responses than other allergens during allergen bronchoprovocation (ABP) testing. The two standardized methods for reporting results of ABP tests are the maximal percent fa...

    Authors: Sarah-Marie Durr, Beth Davis, Gail Gauvreau and Donald Cockcroft
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:8
    Content type: Research Published on:

  6. Allergy immunotherapy (AIT), in the form of subcutaneous immunotherapy (SCIT) with alum-precipitated aqueous extracts, SCIT with a modified ragweed pollen allergen tyrosine adsorbate (MRPATA; Pollinex®-R), or a s...

    Authors: Anne K. Ellis, Douglas P. Mack, Rémi Gagnon, Eva Hammerby and Sheena Gosain
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:7
    Content type: Research Published on:

  7. The diagnosis of food allergy is based on a history of immediate allergic reaction following food ingestion, and skin prick test (SPT) demonstrating sensitization with commercial extracts (CE) or fresh food (F...

    Authors: Idit Lachover-Roth, Nadav Giorno, Tzipi Hornik-Lurie, Anat Cohen-Engler, Yossi Rosman, Keren Meir-Shafrir and Ronit Confino-Cohen
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:6
    Content type: Research Published on:

  8. Oral food challenges (OFC) confer the highest sensitivity and specificity in diagnosis; however, uptake has been variable across clinical settings. Numerous barriers were identified in literature from inadequa...

    Authors: Ala El Baba, Samira Jeimy, Lianne Soller, Harold Kim, Philippe Begin and Edmond S. Chan
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:5
    Content type: Research Published on:

  9. The immunological effect of allergen-specific immunotherapy is well documented, but few studies have examined the long-term effects of pollen subcutaneous immunotherapy (SCIT) on health-related quality of life...

    Authors: Helena Agenäs, Anna Lena Brorsson, Inger Kull and Anna Lindholm-Olinder
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:4
    Content type: Research Published on:

  10. Viable knowledge translation (KT) strategies are increasingly sought to improve asthma diagnosis, particularly in primary care. Despite this understanding, practical KT tools to support primary care practition...

    Authors: Max Moloney, Geneviève Digby, Madison MacKinnon, Alison Morra, David Barber, John Queenan, Samir Gupta, Teresa To and M. Diane Lougheed
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:3
    Content type: Review Published on:

  11. Glucagon-like peptide-1 (GLP-1) receptor agonists are important treatment options in obese patients with type 2 diabetes. To date, few immediate allergic reactions due to GLP-1 receptor agonists were reported....

    Authors: Osman Ozan Yeğit, Göktuğ Sarıbeyliler, Pelin Karadağ, Semra Demir, Nurdan Gül, Derya Ünal and Aslı Gelincik Akkor
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:2
    Content type: Case report Published on:

  12. Asthma is considered to be a chronic inflammatory disorder of the airways. Probiotics are living microorganisms that are found in the human gut and have protective effects against a wide range of diseases such...

    Authors: Sina Sadrifar, Tannaz Abbasi-Dokht, Sarvenaz Forouzandeh, Farhad Malek, Bahman Yousefi, Amir Salek Farrokhi, Jafar Karami and Rasoul Baharlou
    Citation: Allergy, Asthma & Clinical Immunology 2023 19:1
    Content type: Research Published on:

  13. Anxiety and depression can negatively affect the management of asthma. The study aimed to assess the psychosocial effects of asthma patients during COVID-19 and analyze potential risk factors and interventions.

    Authors: Angyang Cao, Yanling Zhou, Wenjun Luo, Dan Lv, Zhonghao Shao, Binbin Zhu and Jianhua Wang
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:113
    Content type: Short Report Published on:

  15. Bullous pemphigoid is the most common autoimmune subepidermal blistering disorder with a low incidence in childhood. Combined immunodeficiencies (CIDs) are a group of monogenic inborn errors of immunity (IEIs)...

    Authors: Mazdak Fallahi, Mahnaz Jamee, Javad Enayat, Fahimeh Abdollahimajd, Mehrnaz Mesdaghi, Maliheh Khoddami, Anna Segarra-Roca, Alexandra Frohne, Jasmin Dmytrus, Mohammad Keramatipour, Mahboubeh Mansouri, Golnaz Eslamian, Shahrzad Fallah, Kaan Boztug and Zahra Chavoshzadeh
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:111
    Content type: Case Report Published on:

  16. Understanding the impact of different immunoglobulin (Ig) infusion methods (intravenous [IVIg] and subcutaneous [SCIg]) upon treatment experience can potentially facilitate optimization of patient outcomes. He...

    Authors: Rajiv Mallick, Geneviève Solomon, Paul Bassett, Xiang Zhang, Palak Patel and Oleksandra Lepeshkina
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:110
    Content type: Research Published on:

  17. Myopericarditis is a well reported complication associated with SARS-Cov-2 (COVID-19) infection and vaccinations; particularly with mRNA vaccines (BNT162b2 and mRNA-1273), and in the young male population. The...

    Authors: Saima Ahmad, Chino Yuson, Adrianna Le and Pravin Hissaria
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:109
    Content type: Case Report Published on:

  18. Asthma is an important non-communicable disease worldwide. DNA methylation is associated with the occurrence and development of asthma. We are aimed at assuring differential expressed genes (DEGs) modified by ...

    Authors: Zongling Wang, Lizhi Wang, Lina Dai, Yanan Wang, Erhong Li, Shuyuan An, Fengliang Wang, Dan Liu and Wen Pan
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:108
    Content type: Research Published on:

  19. Hypersensitivity reactions (HSR) to antineoplastic agents are an increasing problem, especially when they lead to treatment discontinuation, sometimes without any equivalent therapeutic option. HSR to folinic ...

    Authors: Matveï Apraxine, Marc Van den Eynde, Astrid De Cuyper and Françoise Pirson
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:107
    Content type: Case Report Published on:

  20. Genetic defects in the development, maturation, and/or function of the immune cells can lead to Inborn errors of immunity (IEI) which may predispose patients to malignancies. The overall risk for cancer in chi...

    Authors: Marzieh Tavakol, Samaneh Delavari, Fereshte Salami, Sarina Ansari, Seyed Erfan Rasouli, Zahra Chavoshzadeh, Roya Sherkat, Hamid Ahanchian, Soheila Aleyasin, Hossein Esmaeilzadeh, Nasrin Moazzen, Alireza Shafiei, Farhad Abolnezhadian, Sara Iranparast, Sareh sadat Ebrahimi, Tannaz Moeini Shad…
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:106
    Content type: Research Published on:

  21. IPEX syndrome is an X-linked inborn error of immunity clinically characterized by the triad of: enteropathy, polyendocrinopathy and eczema. However many other clinical presentations lacking the triad above des...

    Authors: Leonardo Oliveira Mendonça, Adriana Pitchon dos Reis Chuster, Mayra Barros Dorna, Samar Freschi Barros, Janaina Baptista Alves, Victor Lucas Gonçalves, Ariana Campos Yang, Jorge Kalil, Myrthes Anna Maragna Toledo-Barros and Cristina Maria Kokron
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:105
    Content type: Case Report Published on:

  22. The antigen avoidance has been used in the diagnosis and treatment of hypersensitivity pneumonitis (HP); however, its usefulness in stable fibrotic HP is controversial.

    Authors: Ryo Okuda, Tamiko Takemura, Tae Iwasawa, Shota Kaburaki, Tomohisa Baba, Eri Hagiwara and Takashi Ogura
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:104
    Content type: Research Published on:

  23. To date, little consideration has been given to access to allergy-related care, despite the fact that food allergy affects a considerable proportion of children. As such, the current study aimed to describe ac...

    Authors: Kaitlyn A. Merrill, Elissa M. Abrams, Sara V. Good, Ruchi S. Gupta, Carina Venter, Tara Lynn M. Frykas, Michael A. Golding and Jennifer L. P. Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:103
    Content type: Letter to the Editor Published on:

  24. In anaphylaxis, the dosing of injectable epinephrine in medical settings has been arbitrarily recommended to be 0.01 mg/kg of body weight. For ethical reasons, there have been no dose–response studies or doubl...

    Authors: Sten Dreborg, Graham Walter and Harold Kim
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:102
    Content type: Review Published on:

  25. Long non-coding RNAs (lncRNAs) have been extensively reported to play critical roles in the pathogenesis of various disease, especially in cancer. However, little is known about the role of lncRNAs in the path...

    Authors: Zhang Xude, Feng Shaojie, Guo Beibei, Liu Jingjing, Xu Donghua and Liu Fengxia
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:101
    Content type: Research Published on:

  26. Sensitization to Ara h 2 has been proposed as a promising biological marker for the severity of peanut allergy and may reduce the need for oral food challenges. This study aimed to evaluate whether peanut oral...

    Authors: Iida Ojaniemi, Susanna Salmivesi, Antti Tikkakoski, Jussi Karjalainen, Lauri Lehtimäki and Rüdiger Schultz
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:100
    Content type: Research Published on:

  27. Self-administered subcutaneous immunoglobulin G (SCIg) reduces nursing time and eliminates the need for treatment at ambulatory care clinics, as compared with clinic-based intravenously administered IgG (IVIg)...

    Authors: Bruce Ritchie, Karen J. B. Martins, Dat T. Tran, Heather Blain, Lawrence Richer and Scott W. Klarenbach
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:99
    Content type: Research Published on:

  28. Risk factors for the pathogenesis of chronic rhinosinusitis (CRS) remain largely undetermined, which is likely due to the heterogeneity of the disease. White blood cell counts have been largely unexplored as a...

    Authors: Thanai Pongdee, Suzette J. Bielinski, Paul A. Decker, Hirohito Kita and Nicholas B. Larson
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:98
    Content type: Research Published on:

  30. Mendelian susceptibility to mycobacterial disease (MSMD) is an uncommon disorder with increased susceptibility to less virulent mycobacteria including bacillus Calmette-Guérin (BCG). Fibrosing mediastinitis (FM) ...

    Authors: Niusha Sharifinejad, Seyed Alireza Mahdaviani, Shahrzad Fallah, Nasrin Khakbazan Fard, Alireza Norouzi, Mahnaz Jamee, Mahnaz Sadeghi-Shabestari, Majid Marjani, Mehran Malekshoar, Parisa Farnia and Ali Akbar Velayati
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:96
    Content type: Case report Published on:

  31. Allergic rhinitis (AR) is frequent in children and adolescents and can severely affect their lives. This article describes the development and validation of a questionnaire to assess treatment needs and benefi...

    Authors: Toni Maria Janke, Elisabeth Eisner, Matthias Augustin and Christine Blome
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:95
    Content type: Research Published on:

  32. Childhood adenoid hypertrophy (AH) is common and is often associated with allergic asthma, resulting in complications like obstructive sleep apnea syndrome (OSAS). Management of the disease and its complicatio...

    Authors: Haijing Sui, Huishan Zhang, Wei Ding, Zuotao Zhao, Jiali Mo, Jiexin Yuan and Leping Ye
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:94
    Content type: Case report Published on:

  33. Idiopathic pulmonary fibrosis (IPF) is a fatal fibrotic lung disease with limited treatment options. Plumbagin (PL) is an herbal extract with diverse pharmacological effects that have been recently used to tre...

    Authors: Saber Mehdizadeh, Marjan Taherian, Paria Bayati, Kazem Mousavizadeh, Salar Pashangzadeh, Ali Anisian and Nazanin Mojtabavi
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:93
    Content type: Research Published on:

  34. The effects of a delayed diagnosis of asthma on lung function in children have not been well investigated. Therefore, a retrospective cohort study was conducted in a children’s hospital to analyse the effect o...

    Authors: Xiaoling Wei, Min Xue, Jinyan Yan, Yuling Han, Yanqin Liu, Miao Liu, Jing Sun, Yun Zhang, Lu Cheng, Xiang Ma and Zhongtao Gai
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:92
    Content type: Research Published on:

  35. Since the first reported case of COVID-19, infections due to the virus have ranged from mild to severe. Patients with inborn errors of immunity are thought to be at increased risk for infections such as COVID-...

    Authors: Babak Aberumand, Ramy Kamal, Brock McKinney and Stephen Betschel
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:91
    Content type: Case report Published on:

  36. The lymphocyte transformation test (LTT) is an in vitro assay used to diagnose drug induced hypersensitivity reactions by detecting the activation and expansion of drug-specific memory T cells to the suspected...

    Authors: Chris Weir, Jamma Li, Richard Fulton and Suran L. Fernando
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:90
    Content type: Research Published on:

  37. Dupilumab-induced ocular surface disease (DIOSD) has been reported in patients with atopic dermatitis treated with dupilumab, and has been recognized as an adverse event of dupilumab. Our objective was to desc...

    Authors: Rumi Adachi, Jun Shoji, Akira Hirota, Akiko Tomioka, Yukiko Tonozuka, Noriko Inada and Satoru Yamagami
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:89
    Content type: Case report Published on:

  38. The proliferation of airway smooth muscle cells (ASMCs) contributes to the contractility and inflammation in the pathophysiology of asthma. This intrigued us to clarify the effect of microRNA (miR)-224-5p on b...

    Authors: Zhifang Zhuang, Yanjuan Zhou, Jiao Xu and Leying Pan
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:88
    Content type: Research Published on:

  39. Immunoglobulin replacement therapy is the standard-of-care treatment for patients with primary immunodeficiency diseases who have impaired antibody production and function. Clinicians and patients may consider...

    Authors: Kristin Epland, Daniel Suez and Kenneth Paris
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:87
    Content type: Review Published on:

  40. Fecal calprotectin (FC) is a noninvasive biomarker for assessing the inflammatory status of the gastrointestinal tract. The aim of this study was to determine the association between FC levels and Eosinophilic...

    Authors: Pejman Rohani, Narjes Raja Beheshti, Hosein Alimadadi and Mohammad Hassan Sohouli
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:86
    Content type: Research Published on:

  41. The COVID-19 pandemic has highlighted disparities in healthcare, particularly in the United States, even though disparities have existed since the organization of the modern healthcare system. Recruitment of p...

    Authors: Timothy J. Craig, Rafael H. Zaragoza-Urdaz, H. Henry Li, Ming Yu, Hong Ren, Salomé Juethner and John Anderson
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:85
    Content type: Short report Published on:

  42. Hereditary angioedema (HAE) is an inherited disease characterized by recurrent angioedema without urticaria or pruritus. The most common types of HAE are caused by deficiency or dysfunction in C1 esterase inhi...

    Authors: Yusuke Ushio, Risa Wakiya, Tomohiro Kameda, Shusaku Nakashima, Hiromi Shimada, Mai Mahmoud Fahmy Mansour, Mikiya Kato, Taichi Miyagi, Koichi Sugihara, Rina Mino, Mao Mizusaki, Emi Ibuki, Norimitsu Kadowaki and Hiroaki Dobashi
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:84
    Content type: Case report Published on:

  43. Reports of allergic reactions to the COVID-19 vaccines have been documented, which may also contribute to hesitancy. Despite the low likelihood that the COVID-19 vaccine will trigger an allergic reaction, we a...

    Authors: Michael A. Golding, Nicole Askin, Ayel Luis R. Batac, Kaitlyn A. Merrill, Elissa M. Abrams, Philippe Bégin, Moshe Ben-Shoshan, Erika Ladouceur, Leslie E. Roos, Vladan Protudjer and Jennifer L. P. Protudjer
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:83
    Content type: Research Published on:

  44. Anti-interferon-gamma autoantibody-associated immunodeficiency syndrome is a rare and underrecognized adult onset immunodeficiency syndrome associated with severe opportunistic infections such as disseminated ...

    Authors: Spencer Boyle, Ashley Hagiya, Minh-Vu H. Nguyen, Howard Liebman and Jin Sol G. Lee
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:82
    Content type: Case report Published on:

  46. COVID-19 presents with a variable clinical course from asymptomatic to severe respiratory distress with nearly 25% mortality in mechanically-ventilated patients. As such, there is uncertainty regarding how hos...

    Authors: Kyle D. Miller, Amie M. Ashcraft, Courtney S. Pilkerton and Carl D. Shrader
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:80
    Content type: Case report Published on:

  47. Asthma, allergic rhinitis and eczema have been identified as the most prevalent childhood allergic diseases. However, the prevalence of these allergic diseases can vary in different regions within a country an...

    Authors: Jagath C. Ranasinghe, Ruchira R. Karunarathne, Thilini S. Munasinghe, Gihani U. Vidanapathirana and Sanath T. Kudagammna
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:79
    Content type: Research Published on:

  48. Oral corticosteroids reduce the antibody titer of the BNT162b2 mRNA vaccine against SARS-CoV-2. To date, the effect of inhaled corticosteroids on antibody titers is unknown.

    Authors: Takeo Nakajima, Tatsuya Nagano, Yoshiharu Miyata, Shoko Murakami, Satoshi Mitsuyuki, Yohei Funakoshi, Kimikazu Yakushijin, Hitoshi Horimoto, Yoshihiro Nishimura and Kazuyuki Kobayashi
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:78
    Content type: Research Published on:

  49. Patterns of aeroallergen sensitization vary by countries. Testing with the minimum number of allergens is important to identify sensitized patients for a cost-effective approach. We aimed to assess the minimal...

    Authors: Prapasri Kulalert, Orapan Poachanukoon, Sira Nanthapisal, Paskorn Sritipsukho, Karnsinee Thanborisutkul, Pasistha Termworasin, Rungrawee Kornsawai and Patcharaporn Punyashthira
    Citation: Allergy, Asthma & Clinical Immunology 2022 18:77
    Content type: Research Published on:

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Allergy, Asthma & Clinical Immunology

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