Table 1 Demographic and clinical characteristics of participants in healthy control, CRS, and CRSwNP groups

Age (years)

41 (33, 49)

42 (32, 53)

43 (33, 53)

0.25

0.33

0.006

0.008

Female, No. (%)

443 (42.90)

420 (33.50)

321(33.40)

< 0.001

< 0.001

< 0.001

0.009

BMI (kg/m²)

24.44 (22.14, 26.93)

24.68 (22.34, 27.00)

24.61 (22.34, 27.00)

0.86

0.93

0.57

0.16

BMI ≥ 24, No. (%)

574 (55.60)

719 (58.30)

562 (58.50)

0.45

0.53

0.17

0.44

Comorbid asthma (%)

-

188 (15.0)

179 (18.6)

-

-

-

-

Serum total IgE (kU/I)

-

73.00 (29.40–173.00)

77.80 (31.50–186.00)

-

-

-

-

Blood white cells count (×10⁹/L)

6.01 (5.11, 7.14)

6.35 (5.42, 7.42)

6.43 (5.45, 7.50)

< 0.001

< 0.001

< 0.001

< 0.001

Blood lymphocytes count (×10⁹/L)

1.99 (1.62, 2.41)

2.05 (1.67, 2.45)

2.06 (1.69, 2.48)

0.11

0.16

0.02

0.44

Blood lymphocytes percent (%)

33.40 (28.43, 38.60)

32.50 (27.20, 37.80)

32.25 (27.40, 37.40)

0.002

0.003

0.001

0.002

Blood neutrophils count (×10⁹/L)

3.52 (2.85, 4.36)

3.51 (2.80, 4.41)

3.57 (2.82, 4.42)

0.95

0.95

0.52

0.31

Blood neutrophils percent (%)

59.00 (53.60, 64.10)

56.10 (50.20, 62.30)

55.90 (50.20, 62.10)

< 0.001

0.009

< 0.001

0.009

Blood monocyte count (×10⁹/L)

0.25 (0.19, 0.34)

0.36 (0.28, 0.46)

0.36 (0.29, 0.46)

< 0.001

< 0.001

< 0.001

< 0.001

Blood monocyte percent (%)

4.08 (3.27, 5.46)

5.70 (4.50, 7.00)

5.70 (4.70, 6.90)

< 0.001

< 0.001

< 0.001

< 0.001

Blood eosinophils count (×10⁹/L)

0.10 (0.06, 0.18)

0.25 (0.12, 0.41)

0.27 (0.14, 0.44)

< 0.001

< 0.001

< 0.001

< 0.001

Blood eosinophils percent (%)

1.70 (1.06, 2.80)

3.80 (1.98, 6.20)

4.20 (2.30, 6.50)

< 0.001

< 0.001

< 0.001

< 0.001