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Table 3 Relationship between maternal smoking during infancy and risk of developing allergic diseases stratified by paternal smoking at 5.5 years of age

From: Maternal smoking during infancy increases the risk of allergic diseases in children: a nationwide longitudinal survey in Japan

 

Maternal smoking (cigarettes/day)

Non-paternal smoking

Paternal smoking

n / N (%)

RR

95% CI

n / N (%)

RR

95%CI

Allergic rhinitis/ Allergic conjunctivitis

0

3,600 / 13,468 (26.7)

1

-

2,002 / 7,206 (27.8)

1

-

 10

30 / 82 (36.6)

1.37

1.03–1.82

200 / 595 (33.6)

1.21

1.07–1.36

 11

8 / 33 (24.2)

0.91

0.50–1.66

54 / 144 (37.5)

1.35

1.09–1.67

Food allergy

0

1,701 / 13,084 (13.0)

1

-

932 / 7,002 (13.3)

1

-

 10

9 / 74 (12.2)

0.94

0.51–1.73

101 / 560 (18.0)

1.36

1.12–1.63

 11

4 / 34 (11.8)

0.9

0.36–2.27

21 / 126 (16.7)

1.25

0.84–1.86

Bronchial asthma

0

2,417 / 13,283 (18.2)

1

-

1,587 / 7,216 (22.0)

1

-

 10

22 / 85 (25.9)

1.42

0.99–2.04

176 / 600 (29.3)

1.33

1.17–1.52

 11

8 / 36 (22.2)

1.22

0.66–2.25

57 / 152 (37.5)

1.71

1.38–2.1

Atopic dermatitis

0

2,001 / 13,156 (15.2)

1

-

1,180 / 7,060 (16.7)

1

-

 10

11 / 78 (14.1)

0.93

0.54–1.61

138 / 581 (23.8)

1.42

1.22–1.66

 11

6 / 35 (17.1)

1.13

0.54–2.34

35 / 131 (26.7)

1.6

1.2–2.13

  1. Abbreviations: N, number of children; RR, risk ratio; CI, confidence interval
  2. Adjusted for child factors (sex, singleton or not, preterm birth and day care attendance), parental factors (maternal age at delivery, maternal educational attainment and paternal educational attainment) and residential area