Fig. 1
From: Drug allergy
Figure adapted from: de Las Vecillas Sánchez et al. [14] and Muraro et al. [9]
Drug allergy classification based on phenotypes and endotypes [9, 14]. AECD: aspirin-exacerbated cutaneous disease; AERD: aspirin-exacerbated respiratory disease; AGEP: acute generalized exanthematous pustulosis; alpha-gal: galactose-alpha-1,3-galactose; COX1: cyclooxygenase-1; DRESS: drug reaction with eosinophilia and systemic symptoms; HLA: human leukocyte antigen; IgE: immunoglobulin E; mAb: monoclonal antibody; MRGPRX2: Mas-related G protein-coupled receptor; NSAID, non-steroidal anti-inflammatory drug; SJS: Stevens-Johnson syndrome; TEN: toxic epidermal necrolysis.