Table 2 SLIT products approved in Canada [6, 13,14,15,16,17]

Oralair^®

grass

5–50

First: 100 IR

Second: 200 IR

Subsequent: 300 IR

• Take initial dose of 100 IR in office, 16 weeks before onset of grass pollen season;

• Take second dose of 200 IR at home the following day;

• Then, take 300 IR per day at home until end of grass pollen season.

Grastek^®

grass

5–65

2800 BAU

• Take initial dose in office, 8–12 weeks before grass pollen season;

• Then, take daily dose at home until end of grass pollen season.

Ragwitek^®

ragweed

5–65

12 amb a 1-U

• Take initial dose in office, 12 weeks before ragweed season;

• Then, take daily dose at home until end of ragweed season.

Acarizax™

dust mite

12–65

12 SQ-HDM^†

• Take initial dose in office, anytime throughout the year;

• Then, take daily dose at home for 3–5 years if effective.

Itulatek^®

birch

18–65

12 SQ-Bet^‡

• Take initial dose in office, 16 weeks before birch pollen season;

• Then, take daily dose at home throughout season.