- BCTT: B-cell targeted therapy; CAR-T-cell: chimeric antigen receptor T-cell; CLL: chronic lymphocytic leukemia; IGRT: immunoglobulin replacement therapy; IVIG: intravenous immunoglobulin; MM: multiple myeloma; PLE: protein-losing enteropathy; RCTs: randomized controlled trials; SCIG: subcutaneous immunoglobulin; SHG: secondary hypogammaglobulinemia