Fig. 1

Up-regulated miR-155 expression in skin tissues of patients with CSU and rat models. (A) The expression level of miR-155 was detected in skin tissues of patients in the normal and CSU groups was detected by RT-qPCR; (B) Histamine release rate in the serum from patients in the normal and CSU groups was measured using histamine release assay; (C) The expression level of miR-155 in skin tissues of rats in each group was detected by RT-qPCR; (D) Histamine release rate of serum from rats in the CSU group and normal group was detected by means of histamine release assay. *P < 0.05, **P < 0.01 vs. normal group; #P < 0.05 vs. NC group, &&P < 0.01 vs. CSU group, ∆P < 0.05 vs. in-miR-155 group. CSU, chronic spontaneous urticaria