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Table 2 Association analysis of mtSNP in AR group and control group

From: Two-stage association study of mitochondrial DNA variants in allergic rhinitis

SNP NO

Gene

Region

Rare Allele

FA

FC

OR (95%CI)

p-value

pBH

pB

MT4715.A/G

ND2

Synonymous

G

4/132

24/108

0.1332(0.04467–0.3973)

0.0003

0.0276

0.0276

MT15487.A/T

CYTB

Synonymous

T

4/132

22/110

0.1494(0.04983–0.4477)

0.000687

0.0316

0.0632

MT7196.C/A

COX1

Synonymous

A

4/132

22/110

0.1494(0.04983–0.4477)

0.000687

0.0211

0.0632

MT302.-/CCC

NONE

Intergenic

CCC

34/102

14/118

2.795(1.417–5.516)

0.003037

0.0699

0.2794

MT6962.G/A

COX1

Synonymous

A

18/118

4/128

5.071(1.652–15.56)

0.004547

0.0837

0.4183

MT10609.T/C

ND4L

Nonsynonymous

C

16/120

4/128

4.5(1.442–14.04)

0.009597

0.1472

0.8829

MT12406.G/A

ND5

Nonsynonymous

A

16/120

4/128

4.5(1.442–14.04)

0.009597

0.1261

0.8829

MT12882.C/T

ND5

Synonymous

T

16/120

4/128

4.5(1.442–14.04)

0.009597

0.1104

0.8829

MT16298.T/C

tRNA-Pro

Intergenic

C

8/128

20/112

0.3442(0.1457–0.8133)

0.01506

0.1111

1.0000

MT13759.G/A

ND5

Nonsynonymous

A

12/124

2/130

6.684(1.445–30.92)

0.01507

0.1000

1.0000

MT16311.T/C

tRNA-Pro

Intergenic

C

26/110

12/120

2.478(1.178–5.213)

0.01682

0.0909

1.0000

MT8584.G/A

ATP6

Nonsynonymous

A

14/122

26/106

0.4546(0.225–0.9186)

0.02805

0.0833

1.0000

MT14668.C/T

ND6

Synonymous

T

34/102

20/112

1.925(1.033–3.587)

0.03914

0.0769

1.0000

MT8414.C/T

ATP8

Nonsynonymous

T

34/102

20/112

1.925(1.033–3.587)

0.03914

0.0714

1.0000

MT16260.C/T

tRNA-Pro

Intergenic

T

4/132

12/120

0.2953(0.09186–0.949)

0.04058

0.0667

1.0000

MT10310.G/A

ND3

Synonymous

A

18/118

8/124

2.461(1.015–5.964)

0.04618

0.0625

1.0000

MT6392.T/C

COX1

Synonymous

C

18/118

8/124

2.461(1.015–5.964)

0.04618

0.0588

1.0000

  1. SNP, single nucleotide polymorphism; MT, mitochondrial; FA, frequency of affected; FC, frequency of control; OR, odd ratio. CI, confidence interval;
  2. pBH, pBonjamini-Hochberg; pB, pBofferoni
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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