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Table 4 Overview of the defining features of innate and adaptive immunity [1]

From: An introduction to immunology and immunopathology

 

Innate immune system

Adaptive immune system

Cells

Hematopoietic cells:

• Macrophages

• Dendritic cells

• Mast cells

• Neutrophils

• Basophils

• Eosinophils

• NK cells

• T cells

Non-hematopoietic cells

• Epithelial cells (skin, airways, gastrointestinal tract)

Hematopoietic cells:

• T cells

• B cells

Molecules

• Cytokines

• Complement

• Proteins and glycoprotein

• Antibodies (Ig)

• Cytokines

Response time

• Immediate

• Delayed by hours to days

Immunologic memory

• None: responses are the same with each exposure

• Responsiveness enhanced by repeated antigen exposure