Table 1 Classification of adverse drug reactions [1, 4, 5]
From: Drug allergy
Type A: Predictable | Type B: Unpredictable |
|---|---|
• Drug overdose • Secondary drug effects • Side effects • Drug interactions | • Drug allergy: an immunologically mediated ADR • Pseudoallergic (non-allergic): a reaction with the same clinical manifestations as an allergic reaction, but that lacks immunological specificity • Drug intolerance: an undesirable pharmacologic effect that occurs at low and sometimes sub-therapeutic doses of the drug that are not caused by underlying abnormalities of metabolism or drug excretion • Drug idiosyncrasy: an abnormal/unexpected effect, usually caused by underlying abnormalities of metabolism, excretion, or bioavailability |